Kräftigung wider das Altern

Zusammenfassung

Mit der steigenden Lebenserwartung und dem demografischen Wandel ist auch ein Panoramawandel in der Gesundheitslandschaft zu verzeichnen. Diese äußert sich in einem Anstieg der Prävalenz von altersassoziierten Erkrankungen, aber auch von Multi-morbidität. Körperliche Aktivität im Allgemeinen, aber auch körperliches Training im Speziellen stellt hierbei ein immens wichtiger protektiver Faktor dar, welcher auch die Selbstständigkeit und körperliche wie geistige Funktion im höheren Alter sichert. In der vorliegenden Übersichtsarbeit wird ein Einblick in die verschiedenen Wirkbereiche von körperlicher Aktivität mit Blick auf die älter werdende Gesellschaft gegeben.

Summary

Increasing life expectancy and demographic change has led to a twist in the range of diseases and disabilities. This is reflected by an increase of age-associated diseases, disabilities and cases of multi-morbidity. Physical activity and physical training are crucial protective factors to face these health-related issues. Especially in the older population, exercise can be an empowerment to maintain physical autonomy and cognitive health. This review provides an insight into the manifold effectiveness of physical activity considering the aging society.

Stichworte

Demografischer Wandel - Polypille Bewegung - Degeneration

Key words

Demographic change - polypill exercise - degeneration

• Literatur

• 1 Bundesamt S. Bevölkerung nach Altersgruppen. 13. koordinierte Bevölkerungsvorausberechnung: Bevölkerung Deutschlands bis 2060. In, Lange Reihen; 2015
• 2 UN. In affairs Populations Ageing and Development In; 2012
• 3 Tanaka H, Seals DR. Invited review: dynamic exercise performance in masters athletes: insight into the effects of primary human aging on physiological functional capacity. Journal of Applied Physiology 2003; 95: 2152-2162
• 4 Pearson SJ, Young A, Macaluso A. et al. Muscle function in elite master weightlifters. Medicine & Science in Sports & Exercise 2002; 34: 1199-1206
• 5 Warming L, Hassager C, Christiansen C. Changes in bone mineral density with age in men and women: a longitudinal study. Osteoporosis International 2002; 13: 105-112
• 6 Andreoli A, Celi M, Volpe SL. et al. Long-term effect of exercise on bone mineral density and body composition in post-menopausal ex-elite athletes: a retrospective study. European journal of clinical nutrition 2012; 66: 69
• 7 Etherington J, Harris PA, Nandra D. et al. The effect of weight‐bearing exercise on bone mineral density: a study of female ex‐elite athletes and the general population. Journal of Bone and Mineral Research 1996; 11: 1333-1338
• 8 Kemmler W, von Stengel S, Engelke K. et al. Exercise effects on bone mineral density, falls, coronary risk factors, and health care costs in older women: the randomized controlled senior fitness and prevention (SEFIP) study. Archives of internal medicine 2010; 170: 179-185
• 9 Zhao R, Zhao M, Xu Z. The effects of differing resistance training modes on the preservation of bone mineral density in postmenopausal women: a meta-analysis. Osteoporosis international 2015; 26: 1605-1618
• 10 Peterson MD, Rhea MR, Sen A, Gordon PM. Resistance exercise for muscular strength in older adults: a meta-analysis. Ageing research reviews 2010; 9: 226-237
• 11 Rhea MR, Alvar BA, Burkett LN, Ball SD. A meta-analysis to determine the dose response for strength development. Med Sci Sports Exerc 2003; 35 (03) : 456-464
• 12 Borde R, Hortobágyi T, Granacher U. Dose-response relationships of resistance training in healthy old adults: a systematic review and meta-analysis. Sports medicine 2015; 45: 1693-1720
• 13 Steib S, Schoene D, Pfeifer K. Dose-response relationship of resistance training in older adults: a meta-analysis. Med Sci Sports Exerc 2010; 42 (05) : 902-914
• 14 Porter MM. Power training for older adults. Applied Physiology, Nutrition, and Metabolism 2006; 31: 87-94
• 15 Hazell T, Kenno K, Jakobi J. Functional benefit of power training for older adults. Journal of Aging and Physical Activity 2007; 15: 349-359
• 16 Tschopp M, Sattelmayer MK, Hilfiker R. Is power training or conventional resistance training better for function in elderly persons? A meta-analysis. Age and ageing 2011; 40: 549-556
• 17 Caserotti P, Aagaard P, Buttrup Larsen J, Puggaard L. Explosive heavy‐resistance training in old and very old adults: changes in rapid muscle force, strength and power. Scandinavian journal of medicine & science in sports 2008; 18: 773-782
• 18 Tieland M, Trouwborst I, Clark BC. Skeletal muscle performance and ageing. Journal of cachexia, sarcopenia and muscle 2018; 9: 3-19
• 19 Kryger AI, Andersen JL. Resistance training in the oldest old: consequences for muscle strength, fiber types, fiber size, and MHC isoforms. Scandinavian journal of medicine & science in sports 2007; 17: 422-430
• 20 Slivka D, Raue U, Hollon C, Minchev K, Trappe S. Single muscle fiber adaptations to resistance training in old (> 80 yr) men: evidence for limited skeletal muscle plasticity. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2008; 295: R273-R280
• 21 Booth FW, Roberts CK, Laye MJ. Lack of exercise is a major cause of chronic dis-eases. Comprehensive Physiology 2012; 2: 1143
• 22 Rütten A, Pfeifer K. Nationale Empfehlungen für Bewegung und Bewegungsförderung. Friedrich-Alexander-Universität Erlangen-Nürnberg, 2016
• 23 Ruiz JR, Sui X, Lobelo F. et al. Association between muscular strength and mortality in men: prospective cohort study. Bmj 2008; 337: a439
• 24 Sasaki H, Kasagi F, Yamada M, Fujita S. Grip strength predicts cause-specific mo-tality in middle-aged and elderly persons. The American journal of medicine 2007; 120: 337-342
• 25 Newman AB, Kupelian V, Visser M. et al. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2006; 61: 72-77
• 26 Leong DP, Teo KK, Rangarajan S. et al. Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study. The Lancet 2015; 386: 266-273
• 27 Köppel M. Der Handgrip – günstiges und einfaches aber auch sinnvolles Assessmentinstrument? In: DVGS-Blog; 2018
• 28 Guadalupe-Grau A, Carnicero JA, Gómez-Cabello A. et al. Association of regional muscle strength with mortality and hospitalisation in older people. Age and ageing 2015; 44: 790-795
• 29 Ling CHY, Taekema D, de Craen AJM. et al. Handgrip strength and mortality in the oldest old population: the Leiden 85-plus study. Canadian Medical Association Journal 2010; 182: 429-435
• 30 Hagstrom AD, Marshall PWM, Lonsdale C. et al. Resistance training improves fatigue and quality of life in previously sedentary breast cancer survivors: a randomised controlled trial. European journal of cancer care 2016; 25: 784-794
• 31 Schmidt ME, Wiskemann J, Armbrust P. et al. Effects of resistance exercise on fatigue and quality of life in breast cancer patients undergoing adjuvant chemotherapy: a randomized controlled trial. International journal of cancer 2015; 137: 471-480
• 32 Steindorf K, Schmidt ME, Klassen O. et al. Randomized, controlled trial of resistance training in breast cancer patients receiving adjuvant radiotherapy: results on cancer-related fatigue and quality of life. Annals of oncology 2014; 25: 2237-2243
• 33 Winters-Stone KM, Dobek J, Nail L. et al. Strength training stops bone loss and builds muscle in postmenopausal breast cancer survivors: a randomized, con-trolled trial. Breast cancer research and treatment 2011; 127: 447
• 34 Brown JC, Schmitz KH. Weight lifting and physical function among survivors of breast cancer: a post hoc analysis of a randomized controlled trial. Journal of Clinical Oncology 2015; 33: 2184
• 35 Galvao DA, Taaffe DR, Spry N. et al. Exercise preserves physical function in prostate cancer patients with bone metastases. Medicine and science in sports and exercise 2018; 50: 393
• 36 Schmitz KH, Ahmed RL, Troxel A. et al. Weight lifting in women with breast-cancer – related lymphedema. New England Journal of Medicine 2009; 361: 664-673
• 37 Courneya KS, Segal RJ, McKenzie DC. et al. Effects of exercise during adjuvant chemotherapy on breast cancer outcomes. Medicine and science in sports and exercise 2014; 46: 1744-1751
• 38 Wiskemann J, Kleindienst N, Kuehl R. et al. Effects of physical exercise on survival after allogeneic stem cell transplantation. International journal of cancer 2015; 137: 2749-2756
• 39 Borson S. Cognition, aging, and disabilities: conceptual issues. Physical medicine and rehabilitation clinics of North America 2010; 21: 375-382
• 40 Colcombe SJ, Kramer AF, Erickson KI, Scalf P. The implications of cortical recruitment and brain morphology for individual differences in inhibitory function in aging humans. Psychology and aging 2005; 20: 363-375
• 41 Harada CN, Natelson Love MC, Triebel KL. Normal cognitive aging. Clinics in Geriatric Medicine 2013; 29: 737-752
• 42 Katoh-Semba R, Wakako R, Komori T. et al. Age-related changes in BDNF protein levels in human serum: differences between autism cases and normal controls. International Journal of Developmental Neuroscience 2007; 25: 367-372
• 43 Törpel A. Zum Einsatz der intermittierenden normobaren Hypoxie in Kombination mit einem Kraftausdauertraining zur Gesundheitsförderung: Analyse hämatologischer, leistungsphysiologischer und neurophysiologischer Adaptationen bei jungen und älteren Menschen: Verlag Dr. Kovač; 2018
• 44 Zigmond MJ, Smeyne RJ. Exercise: is it a neuroprotective and if so, how does it work?. Parkinsonism & related disorders 2014; 20 Suppl (01) : 123-127
• 45 Tuon T, Valvassori SS, Lopes-Borges J. et al. Physical training exerts neuroprotective effects in the regulation of neurochemical factors in an animal model of Parkinson’s disease. Neuroscience 2012; 227: 305-312
• 46 Burns JM, Johnson DK, Watts A. et al. Reduced lean mass in early Alzheimer dis-ease and its association with brain atrophy. Archives of neurology 2010; 67: 428-433
• 47 Tolea MI, Galvin JE. Sarcopenia and impairment in cognitive and physical performance. Clinical interventions in aging 2015; 10: 663-671
• 48 Adamo ML, Farrar RP. Resistance training, and IGF involvement in the maintenance of muscle mass during the aging process. Ageing research reviews 2006; 5: 310-331
• 49 Cotman CW, Berchtold NC, Christie LA. Exercise builds brain health: key roles of growth factor cascades and inflammation. Trends in neurosciences 2007; 30: 464-472
• 50 Suo C, Singh MF, Gates N. et al. Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise. Molecular psychiatry 2016; 21: 1633-1642
• 51 Cassilhas RC, Viana VAR, Grassmann V. et al. The impact of resistance exercise on the cognitive function of the elderly. Medicine and Science in Sports and Exercise 2007; 39: 1401-1407
• 52 Forte R, Boreham CAG, Leite JC. et al. Enhancing cognitive functioning in the elderly: Multicomponent vs resistance training. Clinical interventions in aging 2013; 8: 19-27
• 53 Kimura K, Obuchi S, Arai T. et al. The influence of short-term strength training on health-related quality of life and executive cognitive function. Journal of physiological anthropology 2010; 29: 95-101
• 54 Liu-Ambrose T, Donaldson MG. Exercise and cognition in older adults: Is there a role for resistance training programmes?. British Journal of Sports Medicine 2009; 43: 25-27
• 55 Liu-Ambrose T, Nagamatsu LS, Graf P. et al. Resistance training and executive functions: A 12-month randomized controlled trial. Archives of Internal Medicine 2010; 170: 170-178
• 56 Liu-Ambrose T, Nagamatsu LS, Voss MW. et al. Resistance training and functional plasticity of the aging brain: A 12-month randomized controlled trial. Neurobiology of Aging 2012; 33: 1690-1698
• 57 Smolarek AC, Boiko Ferreira LH, Gomes Mascarenhas LP. et al. The effects of strength training on cognitive performance in elderly women. Clinical interventions in aging 2016; 11: 749-754
• 58 Nagamatsu LS, Handy TC, Hsu CL, Voss M, Liu-Ambrose T. Resistance training promotes cognitive and functional brain plasticity in seniors with probable mild cognitive impairment: A 6-month randomized controlled trial. Archives of internal medicine 2012; 172: 666-668
• 59 Kelly ME, Loughrey D, Lawlor BA. et al. The impact of exercise on the cognitive functioning of healthy older adults: A systematic review and meta-analysis. Ageing research reviews 2014; 16: 12-31
• 60 Vilela TC, Muller AP, Damiani AP. et al. Strength and Aerobic Exercises Improve Spatial Memory in Aging Rats Through Stimulating Distinct Neuroplasticity Mechanisms. Molecular neurobiology 2017; 54: 7928-7937
• 61 Chang YK, Pan CY, Chen FT. et al. Effect of resistance-exercise training on cognitive function in healthy older adults: a review. Journal of aging and physical activity 2012; 20: 497-517
• 62 Loprinzi PD, Addoh O, Joyner C. Multimorbidity, mortality, and physical activity. Chronic illness 2016; 12: 272-280
• 63 Dhalwani NN, O’Donovan G, Zaccardi F. et al. Long terms trends of multimorbidity and association with physical activity in older English population. International Journal of Behavioral Nutrition and Physical Activity 2016; 13: 8
• 64 Loprinzi PD. Associations between bouted and non‐bouted physical activity on multimorbidity. Clinical physiology and functional imaging 2017; 37: 782-784
• 65 Loprinzi PD. Sedentary behavior and medical multimorbidity. Physiology & behavior 2015; 151: 395-397
• 66 Dankel SJ, Loenneke JP, Loprinzi PD. Combined associations of muscle-strengthening activities and accelerometer-assessed physical activity on multimorbidity: findings from NHANES. American Journal of Health Promotion 2017; 31: 274-277
• 67 Huber G. Normalgewicht– das Deltaprinzip: Grundlagen und Module zur Planung von Kursen; mit 14 Tabellen. Köln: Dt. Ärzte-Verl.; 2009